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6-hydroxymethyl-dihydropterin diphosphate biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
7,8-dihydroneopterin <=> glycolaldehyde + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 4.1.2.25 dihydroneopterin aldolase

7,8-dihydroneopterin_3''-triphosphate + H2O <=> H+ + 7,8-dihydroneopterin_3''-phosphate + diphosphate 3.6.1.67 dihydroneopterin triphosphate diphosphatase

2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP <=> H+ + 6-hydroxymethyl-7,8-dihydropterin_diphosphate + AMP 2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase

GTP + H2O <=> 7,8-dihydroneopterin_2,3''-cyclic_phosphate + formate + diphosphate + H+ 3.5.4.16 GTP cyclohydrolase I
3.5.4.39 GTP cyclohydrolase IV


7,8-dihydroneopterin_2,3''-cyclic_phosphate + H2O <=> H+ + 7,8-dihydroneopterin_3''-phosphate 3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase

2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate <=> 7,8-dihydroneopterin_3''-phosphate + H2O 4.2.1.160 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase

7,8-dihydroneopterin_3''-phosphate <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde_phosphate 4.1.2.59 dihydroneopterin phosphate aldolase

GTP + H2O <=> H+ + formate + 7,8-dihydroneopterin_3''-triphosphate 3.5.4.16 GTP cyclohydrolase I

7,8-dihydroneopterin_3''-triphosphate <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde_triphosphate 4.1.2.60 dihydroneopterin triphosphate aldolase

7,8-dihydroneopterin_2,3''-cyclic_phosphate + H2O <=> H+ + 7,8-dihydroneopterin_2''-phosphate 3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase

H2O + GTP <=> H+ + diphosphate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate 3.5.4.25 GTP cyclohydrolase II

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